Therapy The procedure of overdosage with promethazine and phenylephrine is basically symptomatic and supportive. Only in circumstances of utmost overdosage or particular person sensitivity do important indications which includes respiration, pulse, hypertension, temperature, and EKG must be monitored. Activated charcoal orally or by lavage could be supplied, or sodium or magnesium sulfate orally to be a cathartic.
Promethazine is properly absorbed from your gastrointestinal tract. Clinical outcomes are apparent in just 20 minutes after oral administration and usually last 4 to 6 hrs, Whilst They might persist as long as 12 several hours.
Antihistamines are contraindicated for use from the treatment method of lower respiratory tract indications, including asthma.
Akorn lean refers back to the misuse of Akorn promethazine-codeine syrup in lean drinks. Users mix the syrup with soda and sweet to make a sweet, sedative beverage.
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There's two different formulations offered. They meet up with specific individual needs and give healthcare suppliers options in therapy.
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Promethazine really should be utilized cautiously in people with heart problems or impairment of liver operate.
This combination is suitable for many respiratory challenges as it efficiently relieves coughs introduced on by colds, the flu, or allergies.
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Because of the hazards of habit, abuse, and misuse with opioids, even at encouraged doses [see Warnings and Safety measures (five.one)], reserve promethazine HCl and codeine phosphate oral Answer to be used in adult clients for whom the main advantages of cough suppression are anticipated to outweigh the hazards, and in whom an sufficient assessment from the etiology in the cough has actually been manufactured.
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